Oh, my gosh, that's horrible. I've never heard of that before.  I'd always heard that Revolution was safe, relatively speaking.  I hope someone else knows something, and I hope your girly feels better really soon. 

Thanks JR1030.

Mandy, it's possible for my girl to have ingested some but not the first girl. It's really puzzling.
But on a good note, Cande is doing much better, there's not that much blood in her urine tonight. She's more alert and hungry.
Thank god!!

i found this as a list of side effects, but they are most likely only talking about cats and dogs. though i would also have to think they would have done a lot of testing on lab rats too.
"What are the possible side effects of Revolution: Side effects of Revolution that may occur include temporary hair loss at the site of application, loss of appetite, drooling, vomiting, diarrhea, drowsiness, rapid breathing, increased heart rate, and muscle tremors." i also went to check one of my books i have and it says the same thing, but again only talking about cats and dogs


this site list possible causes, (for humans anyways) http://www.emedicinehealth.com/blood_in_the_urine/page2_em.htm

i couldn't really find much info to help but everytime I've used it, i had no problems. hope all ends well

Oh, gosh, I'm so sorry.  I wonder about contamination, too.  Did you use the same batch for yours and your mom's?

I just found my Boo this morning, he has blooding coming from his penis, just like the others. Of course, it can't be the Revolution, it's been almost a full week.
I did some research on hematuria and found Trichosomoides crassicauda (bladder thread worm). Does anyone have any information on this parasite?
I googled it but there's not much. It's species specific, usually no symptoms, mostly found on wild or lab rats not pet rats.
It says treat with ivermectin. I wonder if the Revolution might have had a hand in making the symptoms appear?
I'm still waiting for my vet to come back from her holidays. 

The rats show no pain, wouldn't they be hurting with crystals in the bladder?
I think my vet is in on Monday, if it was something minor, I would have brought them in to the clinic and have her colleague check them out but she really doesn't know much about rats and that would have cost me well over $100 for nothing.
Baytril wouldn't have helped if it were crystals? I'm not even sure if the Baytril did help, it seems that 2 days after the onset of hematuria, the rat is completely back to normal. We start Baytril asap on the one with blood coming from their urethra.

Ratguide says that rats that have eaten a lot of carrots, beets, or berries can show reddish tint in their urine, called pseudohematuria.  Have your rats eaten anything like that?  Ratguide also has a link for trichosomoides crassicauda, but the link goes to a page that doesn't exist.

One thing I read said the threadworms were a chronic condition, and wouldn't bother the rats unless they spread to the lungs.

I read that too. So I think ivermectin might be the best choice. I may also start nebulizing my whole crew again.

Thanks Scout...
I'm calling my vet tomorrow, she should be back. My Boo is not doing so well. He's not bleeding as bad as the other's did but he's lethargic, cold and not eating. I'm really worried about him. 

I made a timeline to get a better idea:

On April 26th, we rescued Daizy and April. (living at my mom's)
On April 27th morning, Daizy gives birth and we then did Revolution on April.
On April 27th evening, we found small spots of blood. I checked April and it was coming from her urethra so she was immediately put on Baytril.
On April 29th, Oscar (lives at my mom's) never had Revolution bled profusely in his cage. He was never in contact with the rescues. We thought Oscar was going to die. (lethargic and cold) We couldn't find any marks on him, and it did not show that he was bleeding from the urethra. We figured he had hurt a toe cause of the amount of blood in the cage and figured it had healed up fast. Full recovery within 24 hours.
June 1st, Revolution on 74 rats.
June 2nd, found Cande,(lives at my place) lethargic, cold and not eating. Lots of blood with urine. I had to change the napkins 4 times. She was put on Baytril immediately and did a full recovery after 3 days.
June 2nd-3rd, Louie (lives at my mom'sand is Oscar's bro) lots of blood, not only urine soaked but if you would pick him up his penis/urethra would gush out blood. Put on Baytril, full recovery within 2 days.
June 4th, I found my Mielle (lives at my place) dying. She is basically brain dead and has huge drops of dark blood coming from her urethra. She passes within a couple of hours.
June 7th, Boo (lives at my place) has some very small amount of blood coming from his urethra. Not much at all. He's on Baytril now. Not recovering well.

I live in a triplex, with my parents and sister. My sister's rats never had any reaction.
But, when my sister gave her dog her revolution (time of month) yesterday, Roxie became very sick. (vomiting and diarrhea)
I don't know if it's all related or just a coincidence, hopefully my vet will have some answers.

oh no, jorats, i'm so sorry about your boo.  he's hale and hearty now at the bridge.