No. And in my opinion, it would take an extraordinarily large dose of orange peel/oil for even a male rat to be effected in any way. D-limonene in the peels of oranges and other citrus fruits causes kidney problems/carcinogenic effects in male rats but d-limonene is mainly in the peel/rind oil of the fruit and in small quantities in mechanically juiced fruit (commercial O.J.) -- this substance which binds to proteins which accumulate in the kidneys in males is thought to eventually build up and cause cancer. - But truthfully- it would take a lot of juice. -Basically replacing water. The actual inside of the fruit is thought to be OK.
*If you are concerned about d-limonene and male rats -- be aware that MANGOES are even higher than orange juice in this substance and it may apply to the whole fruit rather than the rind only.
-- the watchword for all fruits is sparing. One inch pieces, no whole glasses of juice